2-(2-氰基苯)-1,3,2-二氧杂硼己环
吡仑帕奈(Perampanel)相关物质；2-(2-氰基苯)-1,3,2-二氧杂硼己环
2-(2-Cyanophenyl)-1,3,2-dioxaborinane
吡仑帕奈(Perampanel)相关物质；2-(2-氰基苯)-1,3,2-二氧杂硼己环
2-(2-Cyanophenyl)-1,3,2-dioxaborinane
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产品编号： CCR987675
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CAS号： 172732-52-4
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分子式：C10H10BNO2
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分子量：187
英文别名：
2-(1,3,2-Dioxaborinan-2-yl)benzonitrile;
熔点：
54-56°C
可溶性：
Chloroform (Slightly), Methanol (Slightly)
性状：
白色固体
SMILES：
C(C1=C2N=CC=C(C3=CC=CC(NC(=O)C)=C3)N2N=C1)#N
储存条件：
冷藏
参考文献：
Hibi, S. et al.: J. Med. Chem., 55, 10584 (2012); McElhinny, C. et al.: Synthesis, 44, 57 (2012);
2-(2-Cyanophenyl)-1,3,2-dioxaborinane is used in the synthesis of AMPA receptor antagonists in the treatment of neurological diseases causing dysfunction of glutamatergic neurotransmission. Also used in the small scale synthesis of Perampanel (P285520), an AMPA receptor antagonist.
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