6'-氰基-2',3'-二氢-5'-酮代-螺旋[1,3-二氧戊环-2,1'(5'H)-吲哚嗪]-7'-乙酸乙酯
喜树碱衍生物中间体；6'-氰基-2',3'-二氢-5'-酮代-螺旋[1,3-二氧戊环-2,1'(5'H)-吲哚嗪]-7'-乙酸乙酯
6'-Cyano-2',3'-dihydro-5'-oxo-spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic Acid Ethyl Ester
喜树碱衍生物中间体；6'-氰基-2',3'-二氢-5'-酮代-螺旋[1,3-二氧戊环-2,1'(5'H)-吲哚嗪]-7'-乙酸乙酯
6'-Cyano-2',3'-dihydro-5'-oxo-spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic Acid Ethyl Ester
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产品编号： CCR979190
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CAS号： 58610-65-4
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分子式：C15H16N2O5
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分子量：304.3
英文别名：
6'-Cyano-2',3'-dihydro-5'-oxo-spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic Acid Ethyl Ester; NSC 633170
可溶性：
Dichloromethane, Methanol
性状：
绿色固体
SMILES：
N#CC1C=CC2=C([C@@H]([C@H](C(O2)(C)C)O)N2CCCC2)C=1
参考文献：
Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986), Miller, K.D., et al.: Invest. New Drugs, 22, 69 (2004), Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (2004), Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005)
Used in the preparation of Camptothecin derivatives, for their therapeutic use as antitumor agents.
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