考布他汀A4磷酸二钠
康普瑞汀A4磷酸二钠；考布他汀A4磷酸酯二钠盐
Combretastatin A4 Phosphate Disodium Salt
康普瑞汀A4磷酸二钠；考布他汀A4磷酸酯二钠盐
Combretastatin A4 Phosphate Disodium Salt
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产品编号： CCR643025
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CAS号： 168555-66-6
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分子式：C18H19Na2O8P
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分子量：440.29
英文别名：
2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 1-(Dihydrogen phosphate) Sodium Salt; CA 4P;
熔点：
229-233°C
可溶性：
Methanol
性状：
白色固体
SMILES：
CC1=NC=CN1.ClCC1OC1
储存条件：
冷藏
参考文献：
Hamel, E., et al.: Biochem. Pharmacol., 32, 3863 (1983), Chaplin, D.J., et al.: Br. J. Cancer, 74, S86, (1996)
Phosphorylated Combretastatin, a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.
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