朱砂精酸
朱砂精酸
Cinnabarinic Acid
朱砂精酸
Cinnabarinic Acid
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产品编号： CCR442000
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CAS号： 606-59-7
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分子式：C14H8N2O6
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分子量：300.22
英文别名：
2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic Acid; Cinnabaric Acid;
可溶性：
DMSO (Slightly)
性状：
Dark Red to Very Dark Brown Solid
SMILES：
CCOC1=CC(N)=C([N+]([O-])=O)C=C1C(NC1CCN(CC2CCC=CC2)CC1)=O
储存条件：
冷藏
参考文献：
Osiadacz, J., et al.: J. Biotechnol., 72, 141 (1999), Kumar, D., et al.: Bioorg. Med. Chem., 10, 3997 (2002), McCleland, B., et al.: Bioorg. Med. Chem. Lett., 17, 1713 (2007),
A natural phenoxazinone derivative, Cinnabarinic acid is obtained in vitro with aid of laccase by oxidative dimerization of 3-Hydroxyanthranilic acid (a metabolite of the amino acid Trytophan). Cinnabarinic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase.
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