西多福韦
西多福韦水合物
Cidofovir Hydrate
西多福韦水合物
Cidofovir Hydrate
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产品编号： CCR433500
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CAS号： 113852-37-2
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相关CAS号：anhydrous: 113852-37-2
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分子式：C8H14N3O6P.XH2O
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分子量：279.19
英文别名：
[[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic Acid Hydrate; 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine Hydrate; (S)-[[2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic Acid Hydrate; (S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine Hydrate; (S)-HPMPC Hydrate; Cidovir Hydrate; GS 0504 Hydrate; Vistide Hydrate;
熔点：
>250°C (dec.)
可溶性：
DMSO (Sparingly), Water (Sparingly)
性状：
White Solid
SMILES：
OC(C1O[C@H](ON2C(=O)C=C(C)C=C2C2CCCCC2)C(O)C(O)[C@H]1O)=O
储存条件：
冷藏
参考文献：
Rahal, F.M. et al.: Ann. Internal Med., 125, 98 (1996); Johnson, J.A. et al.: Antimicrob. Agents Chemother., 43, 1190 (1999); Ho, H.T. et al.: Mol. Pharmacol., 41, 197 (1992);
An injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. It is used in the treatment of acyclovir resistant herpes as well as a complementary intralesional therapy against papillomatosis caused by human papillomavirus (HPV).
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