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4-氯苯基-2-吡啶甲醇
4-氯苯基-2-吡啶甲醇;α-(4-氯苯基)-2-吡啶甲醇
4-Chlorophenyl-2-pyridinylmethanol
  • 产品编号: CCR379615

  • CAS号: 27652-89-7

  • 分子式:C12H10ClNO

  • 分子量:219.67

  • EINECES:248-592-1

英文别名:
α-(p-Chlorophenyl)-2-pyridinemethanol; (p-Chlorophenyl)(2-pyridinyl)methanol; NSC 31264; NSC 47970
熔点:
77-79˚C
可溶性:
Chlorofrom, DMSO, Methanol
性状:
Off-White to Grey Solid
SMILES:
ClC1C=CC(C(C2C=CC=CN=2)O)=CC=1
储存条件:
冷藏
参考文献:
Ohashi, R., et al.: Drug Metab. Disp., 34, 793 (2006); Reddy, M., et al.: Orient. J. Chem., 23, 691 (2007); Schlichting, D.: J. Pharm. Sci., 51, 134 (1962)
α-(4-Chlorophenyl)-2-pyridinemethanol is used as a reagent in the synthesis of Carbinoxamine (Maleate salt: C175920), a histamine H1 antagonist. α-(4-Chlorophenyl)-2-pyridinemethanol is also an intermediate in the synthesis of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity.
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