1-(3-氯苯基)哌嗪-d8
曲唑酮代谢物内标物；萘法唑酮代谢物内标物；依托哌酮代谢物内标物；1-(3-氯苯基)哌嗪-d8
1-(3-Chlorophenyl)piperazine-d8
曲唑酮代谢物内标物；萘法唑酮代谢物内标物；依托哌酮代谢物内标物；1-(3-氯苯基)哌嗪-d8
1-(3-Chlorophenyl)piperazine-d8
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产品编号： CCR379592
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CAS号： 1189923-43-0
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相关CAS号：13078-15-4（未标记）
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分子式：C10H5D8ClN2
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分子量：204.73
英文别名：
1-(m-Chlorophenyl)piperazine-d8; 4-(3-Chlorophenyl)piperazine-d8; N-(3-Chlorophenyl)piperazine-d8; N-(m-Chlorophenyl)piperazine-d8; NSC 49307-d8; mCPP-d8;
可溶性：
Chloroform, Methanol
性状：
Cleat Colorless to Yellow Oil to Yellow Solid
SMILES：
ClC1C=C(N2C([2H])C([2H])([2H])N([2H])C([2H])([2H])C2([2H])[2H])C=CC=1
储存条件：
冷藏
参考文献：
Melzacka, M., et al.: Pol. J. Pharmacol Pharm., 32, 551 (1980), Fong, M.H., et al.: J. Pharm. Pharmacol., 34, 674 (1982), Fiorella, D., et al.: Psychopharmacology, 119, 220 (1995), Maes, M., et al.: J. Clin. Psychopharmacol., 17, 358 (1997), Bo Wen, et al
It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
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