丙酸氯硫卡松
丙酸氟替卡松中间体；丙酸氯硫卡松
Cloticasone Propionate
丙酸氟替卡松中间体；丙酸氯硫卡松
Cloticasone Propionate
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产品编号： CCR369160
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CAS号： 80486-69-7
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分子式：C25H31ClF2O5S
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分子量：517.03
英文别名：
5-Chloromethyl 6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy) -androsta-1,4-diene-17β-carbothioate; (6α.,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16 -methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-(Chloromethyl) Ester; CCI 18773;
熔点：
>200°C
可溶性：
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
性状：
White to Off-White Solid
SMILES：
ClCSC(=O)[C@]1(OC(=O)CC)[C@]2(C)[C@@H](C[C@H]1C)[C@H]3[C@@]([C@@H](O)C2)(F)[C@]4(C)C(=CC(=O)C=C4)[C@@H](F)C3
储存条件：
冷藏
参考文献：
Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)
An intermediate in the synthesis of Fluticasone Propionate.
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