Δ2-头孢呋辛酯
头孢呋辛前体；Δ2-头孢呋辛酯
Δ2-Cefuroxime Axetil
头孢呋辛前体；Δ2-头孢呋辛酯
Δ2-Cefuroxime Axetil
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产品编号： CCR248070
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CAS号： 123458-61-7
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分子式：C20H22N4O10S
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分子量：510.47
英文别名：
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester
熔点：
64-71°C
可溶性：
DMSO (Slightly), Methanol (Slightly)
性状：
Off-White to Pale Yellow Solid
SMILES：
CO/N=C(\C(N[C@@H]1C(=O)N2C(C(=CS[C@H]12)COC(=O)N)C(OC(OC(=O)C)C)=O)=O)/C1=CC=CO1
储存条件：
-20°C
参考文献：
Nguyen, N., et al.: Pharm. Res., 8, 893 (1991), Stoeckel, K., et al.: Antimicrob. Agents Chemother., 42, 2602 (1998), Scott, L., et al.: Drugs, 61, 1455 (2001),
Δ2-Cefuroxime Axetil (Cefuroxime Axetil EP Impurity A) is an oral prodrug of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester is applied in therapy as a mixture of the R and S diastereoisomers.
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