头孢呋辛酯
头孢呋辛酯
Cefuroxime Axetil
头孢呋辛酯
Cefuroxime Axetil
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产品编号： CCR248065
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CAS号： 64544-07-6
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分子式：C20H22N4O10S
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分子量：510.47
英文别名：
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester; Altacef; Bioracef; CCI 15641; Cefaks; Cefazine; Ceftin; Cefurax; Cefuroxime 1-Acetoxyethyl Ester; Elobact; Forcef; Oraxim; Zinat; Zinnat;
熔点：
108-120°C
可溶性：
DMSO (Sparingly), Methanol (Sparingly)
性状：
White to Pale Yellow Solid
SMILES：
CO/N=C(\C(N[C@@H]1C(=O)N2C(=C(CS[C@H]12)COC(=O)N)C(OC(OC(=O)C)C)=O)=O)/C1=CC=CO1
储存条件：
-20°C
参考文献：
Nguyen, N., et al.: Pharm. Res., 8, 893 (1991), Stoeckel, K., et al.: Antimicrob. Agents Chemother., 42, 2602 (1998), Scott, L., et al.: Drugs, 61, 1455 (2001), Bulitta, J. B., et al.: Antimicrob. Agents Chemother., 53, 3462 (2009);
It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial.
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