(S)-Carisbamate
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(S)-Carisbamate
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(S)-Carisbamate
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产品编号： CCR183510
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CAS号： 194085-75-1
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分子式：C9H10ClNO3
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分子量：215.63
英文别名：
(1S)-1-(2-Chlorophenyl)-1,2-ethanediol 2-Carbamate; JNJ 10234094; RWJ 333369; YKP 509;
熔点：
131-132°C
可溶性：
DMSO (Slightly), Methanol (Slightly)
性状：
White Solid
SMILES：
NC(OCC(C1=CC=CC=C1Cl)O)=O
储存条件：
冷藏
参考文献：
Novak GP, et al. 2007. Neurotherapeutics. Jan;4(1):106-9 PMID: 17199023 Nau C, 2004. J Membr Biol. Sep 1;201(1):1-8 PMID: 15635807 Codd EE, 2008. Pain. Feb;134(3):254-62. Epub 2007 May 25 PMID: 17532139
Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.
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