(R)-Carisbamate
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(R)-Carisbamate
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(R)-Carisbamate
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产品编号： CCR183505
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CAS号： 194085-74-0
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分子式：C9H10ClNO3
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分子量：215.63
英文别名：
(1R)-1-(2-Chlorophenyl)-1,2-ethanediol 2-Carbamate;
熔点：
131-133°C
可溶性：
Chloroform (Slightly), DMSO (Slightly)
性状：
White Solid
SMILES：
C1=CC(C(O)COC(N)=O)=C(Cl)C=C1
储存条件：
-20°C
参考文献：
Novak GP, et al. 2007. Neurotherapeutics. Jan;4(1):106-9. PMID: 17199023 Nau C, 2004. J Membr Biol. Sep 1;201(1):1-8. PMID: 15635807 Codd EE, 2008. Pain. Feb;134(3):254-62. Epub 2007 May 25 PMID: 17532139
Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.
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