CH5424802
间变性淋巴瘤激酶抑制剂；ALK抑制剂
CH5424802
间变性淋巴瘤激酶抑制剂；ALK抑制剂
CH5424802
-
产品编号： CCR183360
-
CAS号： 1256580-46-7
-
分子式：C30H34N4O2
-
分子量：482.62
英文别名：
9-ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzocarbazole-3-carbonitrile
熔点：
274-276°C
可溶性：
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
性状：
White to Off-White Solid
SMILES：
N#CC1C=CC2C3C(=O)C4C=C(C(=CC=4C(C)(C)C=3NC=2C=1)N1CCC(N2CCOCC2)CC1)CC
储存条件：
冷藏
参考文献：
Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);
CH5424802 is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. CH5424802 have been clinically evaluated for the treatment of patients with ALK-driven tumors.
搜索质检报告(COA)
搜索MSDS
