Calindol Hydrochloride
(R)-2-[[[1-(1-萘)乙基]氨基]甲基]-1H-吲哚盐酸盐
Calindol Hydrochloride
(R)-2-[[[1-(1-萘)乙基]氨基]甲基]-1H-吲哚盐酸盐
Calindol Hydrochloride
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产品编号： CCR148700
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CAS号： 729610-18-8
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相关CAS号：Free Base: 374933-30-9
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分子式：C21H21ClN2
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分子量：336.86
英文别名：
N-[(1R)-1-(1-Naphthalenyl)ethyl]-1H-indole-2-methanamine Hydrochloride; (R)-2-[[[1-(1-Naphthyl)ethyl]amino]methyl]-1H-indole Hydrochloride;
熔点：
197-200°C
可溶性：
Chloroform (Slightly), Methanol (Slightly)
性状：
Off-White to Light Pink Solid
SMILES：
Cl.C[C@H](C1=C2C(C=CC=C2)=CC=C1)NCC1NC2C(=CC=CC=2)C=1
储存条件：
冷藏
参考文献：
Fawzi, A., et al.: Biochemistry, 29, 3804 (1990), Han, G., et al.: J. Biol. Chem., 274, 10008 (1999), Palczewski, K., et al.: Science, 289, 739 (2000), Nemeth, E., et al.: J. Pharmacol. Exp. Ther., 299, 323 (2001), Kew, J., et al.: Pharmacol. Ther., 104,
A new calcimimetic acting at the calcium sensing receptor; a positive allosteric modulator of the human Ca2+ receptor, activates an extracellular ligand-binding domain-deleted Rhodopsin-like seven-transmembrane structure in the absence of Ca2+.
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