钙黄绿素AM
钙黄绿素AM
钙黄绿素AM;钙黄绿素乙酸甲酯
Calcein AM
钙黄绿素AM;钙黄绿素乙酸甲酯
Calcein AM
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产品编号: CCR125400
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CAS号: 890090-35-4
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相关CAS号:Component: 148504-34-1
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分子式:C46H46N2O23
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分子量:994.86
英文别名:
N,N’-[[3’,6’-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9’-[9H]xanthene]-2’,7’-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1’-Bis[(acetyloxy) methyl] Ester; Calcein Acetoxymethyl Ester; NSC 689290;
熔点:
>44°C (dec.)
可溶性:
DMSO (Slightly), Methanol (Slightly)
性状:
Off-White to Pale Beige Solid
储存条件:
-20˚C
参考文献:
Feller, N., et al.: Br. J. Cancer, 72, 543 (1995); Dhar, S., et al.: Eur. J. Pharmacol., 346, 315 (1998); Essodaigui, M., et al.: Biochemistry, 37, 2243 (1998); Lemasters, J.J., et al.: Biochim. Biophys. Acta., 1366,177 (1998);
Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
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